Profilo farmacologico clinico e farmacoeconomico di un gel oftalmico a base di carbomero 974P e PVA (Siccafluid®) nella terapia della cheratocongiuntivite secca

Authors

  • Lorenzo Pradelli Centro di ricerche farmacoeconomiche - Advanced Research Srl

  • Letizia Vacchini Gruppo Multimedica Milano



DOI:

https://doi.org/10.7175/fe.v6i3.834

Keywords:

Dry eye syndrome, Carbomer, Tear film

Abstract

BACKGROUND: The dry eye sindrome refers to a group of disorders of the tear film due to reduced tear production or excessive tear evaporation that is associated with symptoms of ocular discomfort and may cause disease of the ocular surface. Dry eye syndrome varies in severity, duration and etiology. The cornerstone of dry eye syndrome therapies includes the intraocular gel or ophthalmic solutions instillation, reaching correct artificial lubrication. Molecules that can produce a stable lubricating film are the carbomers. METHODS: In the first step of our work we reviewed the data from literature reporting about carbomers’ characteristics in respect to other lacrimal substitutes. Then, a pharmacoeconomical analysis has been performed on ophtalmic gels derived from carbomers 974P and PVA. RESULTS: Dry eye sindrome, if not adequately treated, determines a deterioration of the patient’s quality of life, other than high secondary costs. CONCLUSION: The high therapeutical index of carbomers 974P and PVA-based gels, in addition to the their limited cost (totally free for Sjögren patients in Italy), suggests that this product is characterized by one of the best benefits-to-costs ratios in the treatment of dry eye sindrome.

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Published

2005-09-15

Issue

Vol. 6 No. 3 (2005)

Section

Review (Economic Analysis)

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How to Cite

Profilo farmacologico clinico e farmacoeconomico di un gel oftalmico a base di carbomero 974P e PVA (Siccafluid®) nella terapia della cheratocongiuntivite secca. (2005). Farmeconomia. Health Economics and Therapeutic Pathways, 6(3), 185-196. https://doi.org/10.7175/fe.v6i3.834

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